Atypical HUS or Atypical Hemolytic Uremic Syndrome (aHUS) is a condition that is characterized by the following three signs:
- Hemolysis or fragmentation of the red blood cells
- Thrombocytopenia or a low platelet count
- Declining kidney function
- General feeling of being unwell
- Dark urine
- Nausea, vomiting
- Fatigue, tiredness
- Irritability
- Low Hemoglobin
- Low Platelet Counts
- Fragmented blood cells or schistocytes on the smear
- Genetic mutations
- External causes such as pregnancy or HIV
- Complement Factor H
- Complement Factor H R1/3
- Membrane Cofactor Protein
- Complement Factor I
- Complement Factor B
- Complement C3
- Thrombomodulin